The Thyroid Antibodies panel is a comprehensive test that measures multiple types of autoantibodies directed against thyroid tissue, including thyroid peroxidase (TPO) antibodies and thyroglobulin antibodies. This panel provides a more complete evaluation of autoimmune thyroid disease than testing for individual antibodies alone. The presence of these antibodies indicates an autoimmune attack on the thyroid gland, which is the most common cause of thyroid dysfunction in developed countries. This test is particularly valuable for diagnosing autoimmune thyroid conditions such as Hashimoto's thyroiditis, Graves' disease, and postpartum thyroiditis. The panel helps distinguish between autoimmune thyroid disorders and other causes of thyroid problems, guides treatment decisions, and can predict the likelihood of developing thyroid dysfunction in individuals with a family history of autoimmune thyroid disease.