RheumAssure is a comprehensive panel that combines three specialized tests to improve the diagnosis of rheumatoid arthritis (RA). This panel includes RA Factor, CCP Antibodies (IgG/IgA), and 14-3-3 eta protein, providing enhanced sensitivity and specificity for both established and early RA detection. When used together, these markers can diagnose established RA with 88-96% sensitivity and early RA with 78-92% sensitivity. RA Factor is elevated in established RA, while CCP Antibodies offer higher specificity for RA diagnosis. The 14-3-3 eta protein provides incremental benefit in identifying early RA cases. This comprehensive approach helps healthcare providers make more accurate RA diagnoses, particularly in patients with early symptoms or atypical presentations.