Lipase is an enzyme produced by the pancreas that helps break down dietary fats in the digestive system. This test measures the amount of lipase in the blood and is primarily used to diagnose acute pancreatitis, a serious inflammation of the pancreas. Lipase levels rise more quickly and remain elevated longer than amylase levels in pancreatic disease, making it a more reliable marker for pancreatitis. Elevated lipase levels can also indicate other conditions affecting the pancreas, such as pancreatic cancer, pancreatic cysts, or chronic pancreatitis. This test is commonly ordered when patients present with severe abdominal pain, nausea, vomiting, or other symptoms suggestive of pancreatic disease. Early diagnosis of pancreatitis is crucial for preventing complications and ensuring appropriate treatment.