Testosterone, Total, LC/MS-MS is a highly sensitive and specific test that measures total testosterone levels using liquid chromatography-tandem mass spectrometry technology. This advanced methodology is specifically designed to accurately measure the low testosterone levels found in women, children, adolescents, and hypogonadal men. The test is particularly valuable for evaluating androgen excess in women, which can cause hirsutism, acne, menstrual irregularities, and polycystic ovary syndrome (PCOS). In children, it helps assess delayed or precocious puberty and various developmental disorders. The LC/MS-MS method provides superior accuracy compared to immunoassays, especially for low-level measurements, making it the gold standard for testosterone testing in these populations. This test is essential for diagnosing endocrine disorders and guiding appropriate hormonal therapy.